Ambulatory systems allow the animals unrestrained and untethered freedom of movement at all times. Some European countries have instituted regulatory guidelines which virtually ban tethered infusion in large animals due to the belief that untethered systems put less stress on the animal subjects. New advancements in pump technology, jacket design, catheter material, surgical techniques and the happier appearance of the animals have made this the system of choice for many researchers.The basic ambulatory infusion system includes: infusion pump, jacket, extension line and internal catheter. The ambulatory pump is placed inside a fitted pocket that is attached to the animal’s jacket. An extension line runs through a hole in the back of the pocket from the pump to the catheter. The connection between the pump and catheter depends on which catheter system you choose. There are two internal catheter systems to choose from. The first system is the exteriorized catheter that luer locks to the extension line. The second system is the vascular access port that uses a Huber Needle and extension line. The vascular access port allows for easy access and less chance of infection but involves anchoring the Huber needle to the insertion site.
Having decided on which style of catheter system to use, the biggest decision becomes choosing the appropriate pump. There are a number of high quality pumps to choose from. Many of them provide a wide range of delivery options. Choose a pump that is capable of delivering the appropriate volumes and rates you require; small enough to be carried and has a history of standing up to the rigors of on-animal applications. Keep in mind, the volume of solution to be delivered over the infusion period will often weigh more than the pump itself and must also be carried by the animal.
Below we have assembled the system we recommend using for any continuous infusion study in the beagle dog. We have chosen this representative system based on our personal experience and the successful experiences of our clients.
For more information on selecting the right catheter and pump for your research see the General Principles section at the beginning of this publication or give us a call and we will be happy to assist in putting together the right system for you.
Human quality, FDA approved • Titanium Access port and ChronoFlex Polyurethane catheter
