Maintain healthy and freely-moving rabbits with our ambulatory infusion systems.

We'll help you find a lightweight pump and all the proper accessories to build a safe, successful rabbit ambulatory infusion system.

Ambulatory Infusion System for Rabbits

Ambulatory infusion studies in rabbits require a lightweight pump due to the smaller size of the animal. Because of this, a tethered system is an equally common approach. We can help you customize the options for your protocol, including the catheter, access, pumps and more based on:

  • Volume & Flow Rate
  • Animal Weight
  • Cage/Run Size
  • Long Term or Short Term Study
  • Intermittent or Continuous Catheter Access

To learn more about all options, keep reading below. Or, reach out to our experienced staff for advice.

Build a Rabbit Ambulatory Infusion System

Your step-by-step guide to building a safe, effective ambulatory infusion system for rabbit studies.

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To support healthy rabbits, the total weight of both the pump and the filled reservoir must be less than 10% of the animal body weight. If you cannot find a pump that meets this requirement, while also meeting the volume and flow rate requirements for your study, remember that tethered infusion is still an option.

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  • Extremely lightweight pump is only 141g (not including the filled reservoir)
  • Flow rates from 0.01-35mL/hr
  • 50mL Reservoir
  • BlueTooth + Software Option
  • Small footprint (84.5 x 55 x 42mm) makes it easy to center on the animal
  • Ideal for: this versatile pump is good for animals in a range of sizes, including rabbits that weigh 2kg or less. With flexible flow-rates, and optional software, it's ideal for standard infusion as well as group housing studies.

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  • Same weight and dimensions as the SAI 3D Mini, but with smaller reservoir and lower flow rates
  • Flow rates from 0.005-5mL/hr
  • Suitable for rabbits <2kg
  • 20mL Reservoirs
  • BlueTooth + Software Option
  • Ideal for: CNS studies. This pump is our smallest available due to the small syringe size. It's great for studies that require very low flow rates, such as those used for dosing in the ventricular system for CNS delivery.

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  • Small and lightweight at 382g
  • Can only be used with large rabbits >4kg
  • Flow rates from 0.1-125 ml/hr
  • 50, 100, or 250mL Cassettes
  • Rental Option Available
  • Ideal for: Labs that use a variety of species. It can be used for everything from large rabbits to full size pigs. The range of flow rates and high volume options make it an excellent overall laboratory pump.

Jackets

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The right jacket ensures safety and comfort for the rabbit, but also protects the pump. The jacket needs to be appropriately sized for the animal, and then adjusted to suit your pump type and location. With rabbits, it can be especially challenging to situate the jacket, jacket pocket and pump in a way that centers the weight for the animal.

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  • Flexible and durable design combines lightweight, breathable mesh and soft cotton jersey
  • Leg loops are highly recommended for rabbits
  • Sizing for Rabbits from <2.7kg and >5.4kg
  • Can be color-coded for easy group identification

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  • Removeable pockets can be placed with zip ties and create a flexible jacket configuration
  • Attached pockets are more stable and help distribute the weight for the rabbit
  • Pockets can be insulated to maintain temperature of the infusion solution
  • Custom channels can be placed in the pocket to feed tubing

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  • Add a soft, breathable layer with an undershirt
  • Jackets and undershirts can be customized for easy feeing of fluid lines
  • Create a quick identification system with colored jackets and pockets to track study groups

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For rabbit infusion studies, the most common implant site is the jugular vein, but this depends on both the study needs and the surgeon preference. We offer a wide range of catheter options, and can customize the catheter to suit your needs.

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  • Biocompatible catheters are available in both polyurethane and silicone.
  • Sizes from 3-5 Fr, or custom options available
  • Standard design features suture beads at 5 and 7 cm
  • Optional female luer injection valve
  • Ideal for: mid to long-term studies. While the jugular vein is relatively easy to access, it is more invasive than the ear vein. Use this location when your infusion occurs on multiple days or across a several week span.  

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  • Rounded-tip polyurethane design is our best seller
  • Standard size is 3 Fr, or custom options available
  • Suture beads at 7 and 9 cm, or customize for your protocol
  • Ideal for: Blood collection or infusion. While the jugular vein is easy to access, it can be prone to kinking due to position of the head and neck. The femoral implant is less affected by positional issues.

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  • Biocompatible, polyurethane catheters
  • Includes a guide wire and catheter introducer needle for easy implant
  • Access is through marginal ear vein, but catheter tip is advanced into the jugular vein
  • Ideal for: Short term studies- a few days up to two weeks. The benefit of this approach is that no cut-down surgery is required. However, it can be difficult to protect the tubing for a tethered study and catheter patency is not as reliable as a jugular implant.

Externalization

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How to externalize the catheter is an important, but challenging decision. The most common options include Vascular Access Ports (VAPs) or a luer hub on an externalized catheter. Miniaturized Catheter Access Ports are also growing in popularity for large animals after being originally developed for rodents.

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  • Our most commonly used rabbit VAP is our P.A.S. Port Elite due to the low profile
  • VAPs are situated under the skin
  • A non-coring (Huber) needle is required to access the VAP without causing damage
  • Ideal for: Long term studies with intermittent access, especially if there are several days between access. VAPs are also perfect for studies that require group housing; since the port sits below the skin, it is protected from damage

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  • Hubs are easy to swab for clean access
  • Luer Injection Valves (LIVs) can be accessed with a slip tip or luer-lok syringe- no needles required
  • Ideal for: Shorter term studies. The catheter externalizes outside of the body and this makes it more vulnerable than a VAP. However, externalized catheters can be easier to use for repeated access studies, even if they are long term, since they can be easily accessed. The Luer option is the common approach for Ear Vein Catheterizations.

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  • 1, 2 and 3 port options available
  • SAI buttons incorporate a smooth barb at the catheter connection- this creates the most reliable catheter-to-button connection
  • Ingrowth cuff promotes fast healing and reduces incidence of seromas
  • Ideal for: CABs can work for short or long term studies and for repeated or intermittent access. However, since these were developed for rodents, the tubing diameter can be too small for high flow or high viscosity solutions. Please note- at this time, SAI is unaware of the use of this tool in rabbit models, but the CAB has been used in ferrets and minipigs with success.

Software & Support

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To take your studies to the next level, take advantage of our service and support options. We can help with proprietary software, pump calibration services and rental options that will keep your lab running smoothly.

Software

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  • Compatible with SAI 3D MiniBT and SAI 3D MicroBT pumps only. BT denotes BlueTooth enabled
  • Manage and modify flow rates throughout the study
  • Monitor study progress
  • Export data for reports
  • Ideal for: Studies that require minimal human interaction, such as safety pharmacology or other stress sensitive studies. The low flow rates for these pumps also make them ideal of intrathecal infusion

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Using your pumps properly and keeping them in good working order are essential for successful studies. We offer pump repairs and calibration for a variety of pumps, inlcuding the CADD 6500. We can also help with surgical sevices and equipment training to make sure you get started on the right foot.

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Need to increase capacity without adding to your capital budget? SAI offers a variety of pumps for rent.

  • Rental on a per month basis
  • Pumps arrive ready for immediate use with verification paperwork
  • Add to your current capacity or rent enough to run full studies

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