Swine ambulatory infusion studies are safe and easy, with help from SAI

We'll guide you through the steps so that you can build the pig ambulatory system that suits your study. From choosing an infusion pump, to choosing an implatn site, we're here to help.

Ambulatory Infusion System for Pigs

The basic pig infusion configuration shown here covers a majority of protocols. Pigs are both strong and smart, so it's important to design a system that can withstand their rigors. We can help you customize the options for the catheter, catheter access, pumps and more based on:

  • Volume & Flow Rate
  • Weight of the animal
  • Long Term or Short Term Study
  • Intermittent or Continuous Catheter Access
  • Catheter Implant Location and Type

To learn more about all options, keep reading below. Or, reach out to our experienced staff for advice.

Build a Swine Infusion System

Your step-by-step guide to building a safe, effective ambulatory infusion system for pig studies.

Pumps

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Due to their relatively large size, pigs can carry a variety of pumps and still keep the pump weight below 10% of body weight. But pigs are also well known for using their strength and smarts- and they may try to remove the pump through rubbing and other activities. A robust and well protected pump is essential.

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  • Extremely Lightweight 141g
  • Flow rates from 0.01-35mL/hr
  • 50mL Reservoir
  • BlueTooth + Software Option
  • Rental Option Available
  • Ideal for: this versatile pump is good for animals in a range of sizes due to the low weight and small size. With flexible flow-rates, and software, it's ideal for standard infusion, group housing studies, and safety pharmacology studies.

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  • Extremely Lightweight 141g
  • Flow rates from 0.005-5mL/hr
  • 20mL Reservoirs
  • BlueTooth + Software Option
  • Great for Intrathecal Infusion
  • Ideal for: CNS studies. This pump is our smallest available due to the small syringe sizes. It's great for studies that require very low flow rates, such as those used for dosing in the ventricular system for CNS delivery.

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  • Small and lightweight at 382g
  • Flow rates from 0.1-125 ml/hr
  • 50, 100, or 250mL Cassettes
  • Optional accessories for 250mL+
  • Rental Option Available
  • Ideal for: Labs that use a variety of species. It can be used for everything from large primates to full size pigs. The range of flow rates and high volumes options make it an excellent overall laboratory pump.

Jackets

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The right jacket ensures animal safety and comfort. Pigs are hard on their jackets, but also tend to have a bit more sensitive skin than other species, so the jacket is configured to be both tough, and comfortable.

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  • Lightweight, breathable mesh
  • Sizes from less than 2kg to 25kg
  • Optional clips for collar integration
  • Leg straps can be added for extra security
  • Sizing for dogs and hounds

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  • Removeable or Attached Pockets
  • Protective & insulating options
  • Custom channels to feed tubing
  • Attach 1 or 2, depending on pump and reservoir choices

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  • Undershirts and t-shirts
  • Custom color jackets and pockets
  • All designs completely customizable
  • Pillow collars are highly recommended for extra protection.

Catheter Placement

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For swine infusion studies, the most common implant site is the jugular vein, but this depends on both the study needs and the surgeon preference. Many researchers access the jugular with a percutaneous catheter by using the Seldinger technique. This approach is quick and doesn't require tunneling of the catheter to the scapular region.

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  • Biocompatible catheters are made from PU or Silicone.
  • Sizes from 3-7 Fr, or custom options available
  • Catheter options for both tunneled and percutaneous placement.
  • Optional female luer attachment
  • Ideal for: the jugular vein is relatively easy to access and is ideal for infusion studies. Our range of catheter diameters, lengths and materials make it easy to customize based on your study needs.  

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  • Silicone and polyurethane options are available.
  • Standard sizes from 3-7 Fr, or custom options available
  • All catheters can be customized to fit your species, strain and size requirements.
  • Ideal for: Blood collection or infusion. While the jugular vein is easy to access, it can be prone to kinking due to position of the head and neck. The femoral implant is less affected by positional issues.

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We offer a wide range of standard and customizable catheters for pigs, including:

Externalization

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How to externalize the catheter is an important, but challenging decision. The most common options include Vascular Access Ports (VAPs) or a luer hub on an externalized catheter. For pigs, the VAP can help keep the incision clean, but pigs are well-known for being needle-shy.

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VAPs or Vascular Access Ports are ideal for studies that require intermittent and repeated access to the vascular system.  

  • Most customers prefer the Port-A-Cath VAP due to the larger size- this makes it easier to palpate.
  • VAPs are situated under the skin, so a non-coring (Huber) needle is required to access the port.
  • Ideal for: Long term studies with intermittent access, especially if there are several days between access. VAPs can help to keep the catheter pathway clean since they sit under the skin. However, pigs can be needle-shy and may require additional restraint, training, or analgesic treatment to the site before access.

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Luer Injection Valves (LIV) can be connected to an externalized catheter for quick, clean, easy access.

  • Minimal added volume
  • Hubs are easy to swab for clean access
  • No special tools or needle sticks required
  • Ideal for: Shorter term studies. The catheter externalizes outside of the body and this makes it more vulnerable to damage than a VAP. However, externalized catheters can be easier to use for repeated access studies in pigs- especially since swine can be sensitive to needle-sticks required for the VAP.

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Catheter Access Buttons™ are halfway between a VAP and an externalized catheter. The catheter connection sits beneath the skin, but the access port is externalized.  

  • 1, 2 and 3 port options available
  • SAI buttons incorporate CannuLock™ technology for the most secure catheter connection
  • Ingrowth cuff promotes fast healing with low incidence of seromas
  • Ideal for: Repeated access studies, or animals that are needle-shy. CABs can work for short or long term studies and for repeated or intermittent access. However, since these were developed for rodents, the tubing diameter can be too small for high flow or high viscosity solutions.

Software & Support

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To take your studies to the next level, take advantage of our service and support options. We can help with proprietary software, pump calibration services and rental options that will keep your lab running smoothly.

Software

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  • Compatible with SAI 3D MiniBT and SAI 3D MicroBT pumps only. BT denotes BlueTooth enabled
  • Manage and modify flow rates throughout the study
  • Monitor study progress
  • Export data for reports
  • Ideal for: Studies that require minimal human interaction, such as safety pharmacology or other stress sensitive studies. The low flow rates for these pumps also make them ideal of intrathecal infusion

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Using your pumps properly and keeping them in good working order are essential for successful studies. We offer pump repairs and calibration for a variety of pumps, inlcuding the CADD 6500. We can also help with surgical sevices and equipment training to make sure you get started on the right foot.

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Need to increase capacity without adding to your capital budget? SAI offers a variety of pumps for rent.

  • Rental on a per month basis
  • Pumps arrive ready for immediate use with verification paperwork
  • Add to your current capacity or rent enough to run full studies

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